Side effects of testosterone therapy for women can include acne, extra hair growth, weight gain, and fluid retention. Some women have mood swings and become angry or hostile. In rarer circumstances, women develop deeper voices and baldness. Clitoral enlargement is another rare side effect.

Side effects are relatively uncommon if testosterone is taken at low doses. Too much testosterone, however, increases the chances of side effects.

Doses prescribed for men are not appropriate for women.